THE RELATION OF GERM LINE MOSAICISM TO SOMATIC MOSAICISM IN DROSOPHILA
نویسندگان
چکیده
منابع مشابه
The relation of germ line mosaicism to somatic mosaicism in Drosophila.
HE frequently used sex-linked recessive lethal test based on observing the Tprogeny of the F, I, yeneration provides an objective and sensitive test for F, females having germ lines complete for a lethal mutation on their paternal X chromosome, and applied to the F, generation provides an objective test for F, females with germ lines mosaic for a lethal on their paternal X chromosome. If a muta...
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The large number of cell divisions required to make a human body inevitably leads to the accumulation of somatic mutations. Such mutations cause individuals to be somatic mosaics. Recent advances in genomic technology now allow measurement of somatic diversity. Initial studies confirmed the expected high levels of somatic mutations within individuals. Going forward, the big questions concern th...
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Introduction Familial cold autoinflammatory syndrome, Muckle-Wells syndrome (MWS), and chronic, infantile, neurological, cutaneous and articular (CINCA) syndrome are dominantly inherited autoinflammatory diseases associated to gain-of-function NLRP3 mutations. All these diseases are currently considered as different phenotypes of the cryopyrin-associated periodic syndromes (CAPS). A variable de...
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Linear lichen planus (LP) is a rare dermatologic disease in which lichenoid lesions conform to a blaschkolinear distribution, most commonly on the extremities. Linear discoid lupus erythematosus (DLE) is a cutaneous manifestation of lupus that also conforms to Blaschko’s lines. Blaschkolinear disorders have been shown to result from somatic mosaicism, most recently in nevus sebaceus, epidermal ...
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ژورنال
عنوان ژورنال: Genetics
سال: 1967
ISSN: 1943-2631
DOI: 10.1093/genetics/55.3.619